Carlos Alcaraz, who advanced to the last eight in Cincinnati for the third time, has now won 36 of his last 38 matches.
Playing his first match since injuring his knee at Indian Wells last month, Nadal showed no signs of rust as he raced into a 5-0 lead in the first set on Court Rainier III.
Spain's talisman Rafael Nadal sealed a sixth Davis Cup title for his country on Sunday when they beat Canada 2-0 in the final of the revamped event.
"I think especially Rafa playing singles and doubles almost every day, he's been our MVP this week," Lopez said.
France, who were 2-0 up courtesy of Arthur Rinderknech and Adrian Mannarino, faced little resistance from Ecuador as wins for Benjamin Bonzi and the doubles pair of Pierre-Hugues Herbert and Nicholas Mahut secured victory for the 10-times champions.
Norrie's semi-final opponent will be another American, fourth-seeded Tommy Paul, who crushed Stefan Kozlov 6-3, 6-1 in an all-US matchup.
Holder and top seed Novak Djokovic suffered an almighty scare against South African giant Kevin Anderson before bad light halted play with the score tied at two sets all in their fourth round match at Wimbledon on Monday.
World No 1 Novak Djokovic, on Wednesday, became the first player to earn more than US$100 million in prize money after progressing through to the quarter-finals of the French Open in Paris.
World number one Ash Barty delighted the Memorial Drive crowd by breezing through to the Adelaide International semi-finals with a comfortable 6-3, 6-4 victory over Sofia Kenin on Friday.
World No 1 Novak Djokovic and defending champion Andy Murray produced contrasting performances to secure their berths in the quarter-finals of the Madrid Masters on Thursday.
Bhambri, ranked 116 in the world, had reached the second round when the ATP 250 event was played in Chennai in January 2017.
Roger Federer survived a stern test from Spain's Roberto Bautista Agut to reach the Miami Open quarter-finals on Tuesday, while top-seeded Swiss compatriot Stanislas Wawrinka was eliminated on his birthday.
Punjab Marshalls swept the first home tie 23-15 against Raipur Rangers in possibly the most exciting tie of the Champions Tennis League so far in Chandigarh on Friday.
Second seed and world number 14 Roberto Bautista Agut outclassed Benoit Paire in a lop-sided semi-final to set up the singles title clash of the ATP Chennai Open with young Daniil Medvedev, who rallied to reach his maiden ATP final, in Chennai on Saturday.
American Frances Tiafoe celebrated his 21st birthday by stunning Bulgaria's Grigor Dimitrov 7-5, 7-6(6), 6-7(1), 7-5 in the fourth round of the Australian Open on Sunday.
World number nine Janko Tipsarevic of Serbia made a brilliant recovery from a set down and destroyed his opponent Spaniard Roberto Bautista Agut's game in the next two to clinch his maiden Chennai Open ATP tournament title in four attempts in Chennai.
Stefanos Tsitsipas said that his victory in the final of the Mallorca Championships on Saturday was a major milestone in his career as the Greek claimed his maiden grasscourt title leading up to Wimbledon next week.
Former world number one Novak Djokovic's preparation for next month's Australian Open suffered a blow after he pulled out of the season-opening exhibition event in Abu Dhabi on Friday due to pain in his right elbow.
Kyrgios was due to play Spain's Roberto Bautista Agut in the first round in Rome, but was replaced by lucky loser Alexandr Dolgopolov in the men's draw.
Tsitsipas will play 22nd-seeded Spaniard Roberto Bautista Agut for a place in the semi-finals.
Rafael Nadal returned to Roland Garros after his birthday celebrations and showed no signs of slowing up, railroading compatriot Roberto Bautista Agut 6-1, 6-2, 6-2 in the fourth round on Sunday.
Serena Williams rallied to avoid a stunning upset and secure a 1-6, 6-3, 6-3 semi-final win over Czech qualifier Marie Bouzkova at the Rogers Cup on Saturday, setting up a title showdown with local teenager Bianca Andreescu.
PHOTOS from day four of the Wimbledon championships at the All England Lawn Tennis and Croquet Club in London on Friday.
Spain hope new world number one Carlos Alcaraz will be ready for their Davis Cup tie
Leander Paes celebrated his 42nd birthday by making it to the men's doubles quarter-finals of the ATP Aegon Championships at Queen's Club, on Wednesday.
Italy's Matteo Berrettini beat Brazil's Joao Fonseca to give his side a flying start and Matteo Arnaldi then outlasted Thiago Monteiro to put the hosts into a 2-0 lead.
India's top singles tennis player Somdev Devvarman has been handed a direct entry in the main draw of the ATP Chennai Open tennis tournament after Estonia's Jurgen Zopp pulled out of the event due to a back injury.
Sanam Singh beat Roberto Bautista-Agut of Spain to enter the pre-quarter-finals of the boys' singles at Wimbledon.
Roger Federer reached the Rogers Cup semi-finals on Friday after coming to the net early and often in a straight sets victory over Roberto Bautista Agut on a windy day in Montreal.
Defending champion Stanislas Wawrinka survived some anxious against Gilles Muller before proceeding into the men's singles semi-finals at the ATP Chennai Open tennis tournament.
World number two Rafael Nadal has been named in Spain's squad for their Davis Cup World Group quarter-final against Germany in Valencia next month.
Third seed Andrey Rublev suffered a first round exit after his Qatar Open title, losing to qualifier Quentin Halys 3-6, 6-4, 7-6(5) at the Dubai Open on Tuesday.
Novak Djokovic and Roger Federer notched up contrasting victories to reach the Shanghai Masters quarter-finals on Thursday while David Ferrer fought back from a set down to knock out Andy Murray.
The 45th ranked Kyrgios came back from a set down to beat Serbia's Laslo Djere 5-7, 7-6(1) 7-6(1) on Tuesday and was scheduled to play Spaniard Roberto Bautista Agut next.
Novak Djokovic proved to be a calming influence throughout
Rafael Nadal has been left out of Spain's Davis Cup squad for their World Group first-round match against Croatia this weekend due to fatigue.
A summary of Friday's action in the Davis Cup group stage matches.
Top seed Roger Federer needed less than an hour to dispatch Benoit Paire 6-1, 6-3 and reach the quarter-finals of the Swiss Indoors tournament on Thursday -- treating his home fans to another masterclass.
Brothers Elias and Mikael Ymer comfortably won their singles rubbers against Canada as seven-times champions Sweden made a roaring start in the Davis Cup Finals in Madrid on Thursday.
The 32-year-old three-time Grand Slam champion has not played singles since losing in the Australian Open first round in January.